Provocation of neurocardiogenic syncope by clomipramine administration during the head-up tilt test in vasovagal syndrome
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چکیده
منابع مشابه
Provocation of neurocardiogenic syncope by clomipramine administration during the head-up tilt test in vasovagal syndrome.
OBJECTIVES We sought to test the hypothesis that activation of the serotonergic system in patients with vasovagal syndrome during the head-up tilt test provokes syncope. BACKGROUND Central serotonergic activation participates in the pathogenesis of neurocardiogenic syncope. Drugs increasing serotonin (5-HT) in the central nervous system have not been tested as drug challenges during the head-...
متن کاملHead-up tilt test in complicated neurocardiogenic syncope in children.
To confirm the usefulness of head-up tilt test (HUT) in neurocardiogenic syncope (NCS) with complicating clinical features, retrospective analysis were done on 12 selected children. The age at onset was 12.7 +/- 1.9 (mean +/- SD) years. Associated clinical features were postoperative congenital heart disease (PO CHD) in 3, coexistent arrhythmia in 8 (persistent ventricular arrhythmia during exe...
متن کاملHead-up tilt test with clomipramine challenge in vasovagal syndrome--a new tilt testing protocol.
PURPOSE The aim of the study was to randomly compare clomipramine, used as a challenge-agent during head-up tilt test, with isoproterenol, used in the conventional test, in patients with vasovagal syndrome. SUBJECTS AND METHODS The serotonergic re-uptake inhibitor clomipramine was infused (5mg in 5min) at the start of head-up tilt test (Clom-HUT) in 126 patients (mean age 41+/-16 years) with ...
متن کاملRecurrent vasovagal syncope: comparison between clomipramine and nitroglycerin as drug challenges during head-up tilt testing.
AIMS To compare the responses between clomipramine, a centrally acting substance, and nitroglycerin, with mainly peripheral action, when each drug is used during tilt test for the induction of vasovagal syncope (VVS). METHODS AND RESULTS Hundred patients with recurrent episodes of classical VVS underwent two tilt tests in a randomized sequence. One test included 20 min of tilt at 60 degrees w...
متن کاملHead up tilt test in the diagnosis of neurocardiogenic syncope in childhood and adolescence.
BACKGROUND Neurocardiogenic syncope (NCS) is a common paroxysmal disorder that is often misdiagnosed as a seizure disorder. Head up tilt test (HUTT) has been used to confirm this diagnosis. There is no data available of its use in children / adolescents from India. AIM To study the usefulness of the HUTT in children and adolescents with suspected NCS. SETTINGS AND DESIGN This was a part ret...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2000
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(00)00719-1